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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KPNA2
All Species:
14.55
Human Site:
Y225
Identified Species:
24.62
UniProt:
P52292
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52292
NP_002257.1
529
57862
Y225
M
S
S
L
A
C
G
Y
L
R
N
L
T
W
T
Chimpanzee
Pan troglodytes
XP_001170686
399
43075
R116
N
K
N
P
A
P
P
R
D
A
V
E
Q
I
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_861990
529
57923
Y225
M
S
S
L
A
C
G
Y
L
R
N
L
T
W
T
Cat
Felis silvestris
Mouse
Mus musculus
P52293
529
57910
Y225
L
S
T
L
A
C
G
Y
L
R
N
L
T
W
T
Rat
Rattus norvegicus
Q56R16
536
60281
A230
R
L
T
T
T
R
N
A
V
W
A
L
S
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509792
529
57894
Y225
I
S
S
L
A
C
G
Y
L
R
N
L
T
W
A
Chicken
Gallus gallus
Q5ZML1
538
60176
A232
R
I
T
M
T
R
N
A
V
W
A
L
S
N
L
Frog
Xenopus laevis
P52170
522
57670
W224
G
Y
L
R
N
I
T
W
M
L
S
N
L
C
R
Zebra Danio
Brachydanio rerio
Q503E9
536
59774
A230
R
L
T
T
T
R
N
A
V
W
A
L
S
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52295
522
57803
I218
P
L
S
F
L
R
N
I
V
W
L
M
S
N
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19969
514
56144
N212
I
P
I
G
F
L
R
N
V
T
W
V
I
V
N
Sea Urchin
Strong. purpuratus
XP_788859
520
57200
N216
T
P
V
P
F
L
R
N
V
T
W
T
L
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96321
532
58626
T222
L
S
M
L
R
N
A
T
W
T
L
S
N
F
C
Baker's Yeast
Sacchar. cerevisiae
Q02821
542
60423
A235
K
P
S
L
I
R
T
A
T
W
T
L
S
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.8
N.A.
97.7
N.A.
94.5
48.3
N.A.
87.1
46.2
62.9
48.1
N.A.
50.6
N.A.
44.7
60.8
Protein Similarity:
100
75
N.A.
99.2
N.A.
98.1
65.6
N.A.
95.4
64.1
78.6
66
N.A.
68.2
N.A.
63.3
74.8
P-Site Identity:
100
6.6
N.A.
100
N.A.
86.6
6.6
N.A.
86.6
6.6
0
6.6
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
26.6
N.A.
93.3
33.3
20
26.6
N.A.
26.6
N.A.
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.3
43.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.6
61.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
36
0
8
29
0
8
22
0
0
0
8
% A
% Cys:
0
0
0
0
0
29
0
0
0
0
0
0
0
8
8
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
8
15
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
0
8
0
0
29
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
8
8
0
8
8
0
8
0
0
0
0
8
8
0
% I
% Lys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
15
22
8
43
8
15
0
0
29
8
15
58
15
0
43
% L
% Met:
15
0
8
8
0
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
8
0
8
0
8
8
29
15
0
0
29
8
8
36
15
% N
% Pro:
8
22
0
15
0
8
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
22
0
0
8
8
36
15
8
0
29
0
0
0
0
8
% R
% Ser:
0
36
36
0
0
0
0
0
0
0
8
8
36
8
0
% S
% Thr:
8
0
29
15
22
0
15
8
8
22
8
8
29
0
22
% T
% Val:
0
0
8
0
0
0
0
0
43
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
8
36
15
0
0
29
0
% W
% Tyr:
0
8
0
0
0
0
0
29
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _